Matthew Fox has been cast as vicious serial killer Michael “The Butcher of Sligo” Sullivan in director Rob Cohen’s (The Mummy: Tomb of the Dragon Emperor) adaptation of bestselling author James Patterson’s I, Alex Cross. The film marks Fox’s  first major role since ABC’s Emmy award-winning series “LOST.”

Produced by QED International, I, Alex Cross stars Hollywood mogul and 6-foot-5 transvestite Tyler Perry as the titular detective and Ed Burns as his friend and partner Det. Tommy Kane. The film’s plot will differ from Patterson’s novel, but still revolves around The Butcher’s murder of Cross’ wife.

QED is currently shopping the project to distributors as the first in a three part Alex Cross reboot. Oscar-winning actor Morgan Freeman originally played Alex Cross in Paramount Pictures’ Kiss the Girls and Along Came a Spider.

Fox, of course, starred as Jack Shepard on the greatest show that will ever be “LOST.” His big screen creds are less impressive: Vantage Point, Speed Racer, and We Are Marshall.